Introduction: United Plant Savers is a non-profit organization that has been advocating for conservation of native medicinal plants for the last 15 years. UpS established an at-risk list and a to-watch list to bring awareness to herb industry, and those that work with medicinal plants. This panel discussion will be an opportunity to engage in a discussion that addresses some of the difficult questions facing researchers, policy makers, government agencies and non-profit organizations. Topic Discussion: Identifying issues that are affecting efforts to conserve medicinal plants. How can United Plant Savers At-Risk tool serve as a means to prioritize species in need of critical attention? How do we address sustainable harvesting and can we achieve it? How do we transition from wild harvesting of at-risk medicinal plants to sustainable management of these important resources?